The epidermis is an extraordinary, extended and highly specialised organ that, when stimulated from the outside with aesthetic treatments of an invasive nature such as needles, scalpels, lasers, peeling, fillers, radio-frequencies, stimulate cellular response of a regenerative and/or healing type.
In between the cells of the epidermis there is an amorphous substance rich in glycoproteins and polysaccharides, the extracellular matrix (ECM), a micro-world where density and speed of the biological material are quite remarkable.
Thousands of interactions per second are repeated between the ECM and the specialised cells of the skin. This refers to molecules and messengers which are able to affect, operating on the cytoskeleton that composes the internal structure of the cellular bodies, adaptation and spatiality congenial to the tissues that envelope them, depending on the stimuli they receive.

It is only thanks to this coordinated pace that the cells understand what to do and how to arrange themselves, replicating and specialising themselves as they transform from undifferentiated cells into skin cells. This cellular network consists of actual dynamic phases, both in the method used to arrange and differentiate themselves and in those to eliminate them. The former refer to the repair and healing of cells which boosts, if ECM integrity is maintained, a natural evolution towards the regenerationof theepidermis and collagen. And the latter, among which the most representative being apoptosis, that induces depleted, self-destructive cells to commit suicide. In accordance to the above new knowledge and new visions on the skin organ and its basal structure has now emerged. This implies a more accurate consideration on the way to programme, proceed and apply the right derma-surgical methodologies to tissues and consequently the cells that compose them whose vocation is well known.

The objective would be to assist an ideal tissue regeneration in combating and preventing skin aging and lines. One must understand, however, that in most cases the response belongs to a body that is tired and weary due to age and other elements. We know that the external environment relentlessly contaminates and sabotages our cells due to pollution, oxidation and perpetrated damage to our DNA and immune system. In recent years considerable research studies in the dermatological and molecular biology fields have increasingly focused on the cellular elements that comprise the skin and the fundamental substance that surrounds them, the extracellular matrix. Dermatologists can now operate and treat patients avoiding any incorrect decisions. This paves the way towards new treatments to combat skin pathologies and aging. Studies are focusing on intelligent drugs and high-tech, mini-invasive derma-surgical methodologies which will deliver the ideal treatment and stimuli to achieve appreciable results.
And, over time, combat the degeneration caused by tissue aging in a totally natural manner.